Serodiagnosis of Human Bocavirus Infection

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Serodiagnosis of human bocavirus infection.

BACKGROUND A new human-pathogenic parvovirus, human bocavirus (HBoV), has recently been discovered and associated with respiratory disease in small children. However, many patients have presented with low viral DNA loads, suggesting HBoV persistence and rendering polymerase chain reaction-based diagnosis problematic. Moreover, nothing is known of HBoV immunity. We examined HBoV-specific systemi...

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Human bocavirus (HBoV), discovered in 2005, can cause respiratory disease or no symptoms at all. We confirmed HBoV infection in an 8-month-old girl with hypoxia, respiratory distress, wheezing, cough, and fever. This case demonstrates that lower respiratory tract infection caused by HBoV can lead to severe and life-threatening disease.

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2008

ISSN: 1058-4838,1537-6591

DOI: 10.1086/526532